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DOSAGE AND ADMINISTRATION
Dosage should be adjusted according to the severity of the pain and the response of the patient. However, it should be kept in mind that tolerance to hydrocodone can develop with continued use and that the incidence of untoward effects is dose related. The usual adult dosage is one or two tablets every four to six hours as needed for pain. The total daily dosage should not exceed 8 tablets.
The common side effects of VICODIN include:
Lightheadedness, dizziness, anxiety, nausea, vomiting, upset stomach, drowsiness, constipation, headache, mood changes, blurred vision, ringing in your ears, dry mouth, and difficulty urinating.
This product should not be administered to patients who have previously exhibited hypersensitivity to hydrocodone or acetaminophen. Patients known to be hypersensitive to other opioids may exhibit cross-sensitivity to hydrocodone.
-High doses patients, hydrocodone may produce dose-related respiratory depression by acting directly on the brainstem respiratory center. Hydrocodone also affects the center that controls respiratory rhythm, and may produce irregular and periodic breathing.
-The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury,other intracranial lesions or a preexisting increase inintracranial pressure. Furthermore, narcotics produce adverse reactions, which may obscure the clinical course of patients with head injuries.
-The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions.
-Misuse, Abuse, and Diversion of Opioids: VICODIN tablets contain hydrocodone, an opioid agonist, and are a Schedule III controlled substance. Opioid agonists have the potential for being abused and are sought by abusers and people with addiction disorders, and are subject to diversion.
-VICODIN tablets can be abused in a manner similar to other opioid agonists, legal or illicit. This should be considered when prescribing or dispensing VICODIN tablets in situations where the physician or pharmacist is concerned about an increased risk of misuse, abuse or diversion. WIKI